Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.45 |
| ▸ | RXRB | P28702 | 3/20 | 0.45 |
| ▸ | RXRG | P48443 | 3/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 2/20 | 0.41 |
| ▸ | SELP | P16109 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19753275 | 0.95 | RXRA (0.47) | AKR1C1RXRARXRBRXRGFFAR4 | |
| SCHEMBL30083345 | 0.81 | NPC1 (0.56) | MEN1KMT2ARXRA | |
| SCHEMBL20194925 | 0.81 | NPC1 (0.41) | MEN1KMT2ATSHRFFAR4LMNA | |
| SCHEMBL1464596 | 0.81 | NPC1 (0.56) | MEN1KMT2ARXRA | |
| SCHEMBL1465575 | 0.81 | SMPD1 (0.55) | MEN1KMT2ARXRALMNAL3MBTL1 | |
| SCHEMBL20194922 | 0.81 | MCL1 (0.45) | AKR1C1PTPN1LMNA | |
| SCHEMBL15094956 | 0.80 | KDM4E (0.55) | MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL20482682 | 0.80 | MRGPRX4 (0.48) | AKR1C1RXRARXRBRXRGLTB4R | |
| SCHEMBL1466791 | 0.80 | MRGPRX4 (0.48) | MEN1KMT2ARXRARXRB | |
| SCHEMBL27078205 | 0.79 | MEN1 (0.63) | AKR1C1MEN1KMT2ATSHRFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |