Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676677 | 0.76 | POLB (0.46) | POLBALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL696137 | 0.73 | MEN1 (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL9481311 | 0.73 | MEN1 (0.48) | POLBALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL2844080 | 0.72 | MEN1 (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL2657920 | 0.72 | MEN1 (0.54) | POLBALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL25398811 | 0.71 | SMN1; SMN2 (0.45) | POLBALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL2654211 | 0.71 | KMT2A (0.49) | ALDH1A1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL25309164 | 0.71 | MEN1 (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL18722146 | 0.71 | MEN1 (0.56) | POLBALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL11199790 | 0.71 | MEN1 (0.49) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |