Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SDHB | P21912 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696137 | 0.80 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2MAPTPKM | |
| SCHEMBL2844080 | 0.78 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2MAPTPKM | |
| SCHEMBL11905059 | 0.78 | POLB (0.43) | POLBMEN1KMT2ASMN1; SMN2SDHB | |
| SCHEMBL2852600 | 0.78 | L3MBTL1 (0.64) | POLBMEN1KMT2AMAPTGAA | |
| SCHEMBL2657920 | 0.78 | MEN1 (0.54) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL18722146 | 0.77 | MEN1 (0.56) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11199790 | 0.77 | MEN1 (0.49) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL25309164 | 0.77 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2MAPTPKM | |
| SCHEMBL2654211 | 0.77 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2MAPTPKM | |
| SCHEMBL2846375 | 0.76 | POLB (0.42) | POLBMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |