Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30431181 | 0.80 | CYP11B2 (0.44) | PDK2NR1H2LMNAMAPTRAB9A | |
| SCHEMBL13806435 | 0.76 | CYP1A2 (0.46) | HPGDGAAKMT2ATLR9 | |
| SCHEMBL21603396 | 0.73 | SMN1; SMN2 (0.42) | PDK2NR1H2LMNAMAPTRAB9A | |
| SCHEMBL19329523 | 0.71 | CYP1A2 (0.50) | PDK2LMNAMAPTRAB9AKDM4E | |
| SCHEMBL14223471 | 0.71 | PDK2 (0.42) | PDK2NR1H2LMNAMAPTRAB9A | |
| SCHEMBL27174130 | 0.71 | CYP2A6 (0.54) | LMNAMAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL3779423 | 0.70 | MAPT (0.60) | LMNAMAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL11950500 | 0.70 | MAPT (0.60) | LMNAMAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL7419083 | 0.69 | NR1H2 (0.39) | PDK2NR1H2KDM4EALDH1A1HPGD | |
| SCHEMBL2616872 | 0.68 | HSD17B3 (0.59) | PDK2NR1H2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111788183-B | Heterocyclic fused phenyl compounds useful for inhibiting TNIK and medical uses thereof | 韩国化学硏究院 | 2024-02-23 | — | — | CN | disclosed |
| CN-111788183-A | Heterocyclic fused phenyl compounds for inhibiting TNIK and medical uses thereof | 韩国化学硏究院 | 2020-10-16 | — | — | CN | disclosed |