Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.42 |
| ▸ | TTR | P02766 | 5/20 | 0.40 |
| ▸ | EYA3 | Q99504 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20181603 | 0.84 | SLC22A12 (0.46) | SLC22A12TTREYA3CYP2C9CYP2C19 | |
| SCHEMBL24592873 | 0.84 | SLC22A12 (0.38) | SLC22A12EYA3CYP2C9ALDH1A1LMNA | |
| SCHEMBL28464553 | 0.81 | SLC22A12 (0.41) | SLC22A12TTREYA3CYP2C9CYP2C19 | |
| SCHEMBL28468102 | 0.78 | SLC22A12 (0.41) | SLC22A12TTREYA3CYP2C9CYP2C19 | |
| SCHEMBL28467063 | 0.77 | TTR (0.43) | SLC22A12TTREYA3CYP2C9CYP2C19 | |
| SCHEMBL19531525 | 0.76 | KDM4E (0.44) | ALDH1A1HPGDMEN1POLBADORA3 | |
| SCHEMBL28470517 | 0.76 | SLC22A12 (0.49) | SLC22A12TTREYA3CYP2C9CYP2C19 | |
| SCHEMBL28462692 | 0.75 | TTR (0.44) | SLC22A12TTREYA3CYP2C9CYP2C19 | |
| SCHEMBL21584617 | 0.70 | PTGDR2 (0.37) | SLC22A12CYP2C9CYP2C19ALDH1A1MEN1 | |
| SCHEMBL21584605 | 0.69 | ELANE (0.41) | ALDH1A1LMNAADORA3MAPTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759588-B | Phenyl- (pyrazolo [1,5-a ] pyridine-3-yl) ketone derivative | 江苏新元素医药科技有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-107759588-B | Phenyl- (pyrazolo [1,5-a ] pyridine-3-yl) ketone derivative | 江苏新元素医药科技有限公司 | 2020-10-23 | — | — | CN | disclosed |