Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.46 |
| ▸ | EYA3 | Q99504 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | EYA2 | O00167 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464553 | 0.93 | SLC22A12 (0.41) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28467063 | 0.92 | TTR (0.43) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28462692 | 0.91 | TTR (0.44) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28464628 | 0.84 | SLC22A12 (0.42) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL20181600 | 0.82 | MIF (0.43) | SLC22A12EYA3CYP2C9CYP2C19MEN1 | |
| SCHEMBL28468102 | 0.81 | SLC22A12 (0.41) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28462699 | 0.81 | TTR (0.43) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28470517 | 0.79 | SLC22A12 (0.49) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28470057 | 0.79 | MAPT (0.37) | SLC22A12CYP2C9CYP2C19MEN1ALDH1A1 | |
| SCHEMBL28899497 | 0.78 | SLC22A12 (0.41) | SLC22A12EYA3CYP2C9TTRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759588-B | Phenyl- (pyrazolo [1,5-a ] pyridine-3-yl) ketone derivative | 江苏新元素医药科技有限公司 | 2020-10-23 | — | — | CN | claimed |
| US-RE50083-E1 | URAT1 inhibitor and use thereof | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2024-08-20 | — | — | US | disclosed |
| EP-3543240-B1 | URAT1 INHIBITOR AND USE THEREOF | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3543240-B1 | URAT1 INHIBITOR AND USE THEREOF | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2022-07-06 | — | — | EP | disclosed |
| US-10875865-B2 | URAT1 inhibitor and use thereof | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2020-12-29 | — | — | US | disclosed |
| CN-107759588-B | Phenyl- (pyrazolo [1,5-a ] pyridine-3-yl) ketone derivative | 江苏新元素医药科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| US-20200062763-A1 | URAT1 INHIBITOR AND USE THEREOF | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2020-02-27 | — | — | US | disclosed |
| WO-2018090921-A1 | URAT1 INHIBITOR AND USE THEREOF | 江苏新元素医药科技有限公司 | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062763-A1 | URAT1 INHIBITOR AND USE THEREOF | SLC14A1, SLC10A6, SLC10A1 | SLC22A12 39/4885EYA3 2921/4885CYP2C9 3106/4885 |
| US-10875865-B2 | URAT1 inhibitor and use thereof | SLC14A1, SLC10A6, SLC10A1 | SLC22A12 39/4885EYA3 2921/4885CYP2C9 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.