Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22056908 | 0.84 | MEN1 (0.51) | MEN1KMT2AAHRMAPTNPC1 | |
| SCHEMBL5656811 | 0.81 | MEN1 (0.51) | MEN1KMT2AAHRMAPTNPC1 | |
| SCHEMBL22056715 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2AAHRMAPTNPC1 | |
| SCHEMBL8399451 | 0.78 | POLB (0.51) | MEN1KMT2AAHRMAPTTHRB | |
| SCHEMBL4572858 | 0.77 | MEN1 (0.44) | MEN1KMT2AAHRMAPTNPC1 | |
| SCHEMBL29776216 | 0.76 | KMT2A (0.54) | MEN1KMT2AAHRMAPTNPC1 | |
| SCHEMBL10517153 | 0.76 | KMT2A (0.54) | MEN1KMT2AAHRMAPTNPC1 | |
| SCHEMBL3970809 | 0.73 | AHR (0.41) | MEN1KMT2AAHRMAPTNPC1 | |
| SCHEMBL28463061 | 0.71 | MAPT (0.52) | MEN1KMT2AMAPTTHRBALDH1A1 | |
| SCHEMBL6039621 | 0.70 | KMT2A (0.75) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553607-B | Pyrimidine carboxamide derivatives, preparation method, composition, preparation and application thereof | 镇江圣安医药有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-109553607-B | Pyrimidine carboxamide derivatives, preparation method, composition, preparation and application thereof | 镇江圣安医药有限公司 | 2020-09-01 | — | — | CN | disclosed |