Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.65 |
| ▸ | PPARD | Q03181 | 1/20 | 0.65 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.65 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29196173 | 1.00 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL16860501 | 1.00 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL10736739 | 1.00 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL7971309 | 0.98 | LCK (0.61) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL4414310 | 0.98 | LCK (0.61) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| Bromide SCHEMBL9427462 | 0.95 | LCK (0.59) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL7971596 | 0.90 | — | — | |
| SCHEMBL3875750 | 0.90 | — | — | |
| SCHEMBL9621074 | 0.90 | LCK (0.77) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL22826569 | 0.90 | LCK (0.77) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825653-A | Preparation of substituted pyrazoles and use thereof as anthranilamide precursors | 安道麦马克西姆有限公司 | 2020-10-27 | — | — | CN | disclosed |