Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | PPARD | Q03181 | 1/20 | 0.61 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.61 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 3/20 | 0.30 |
| ▸ | ARG2 | P78540 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414310 | 1.00 | LCK (0.61) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL10736739 | 0.98 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL28464686 | 0.98 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| Bromide SCHEMBL9427462 | 0.98 | LCK (0.59) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL16860501 | 0.98 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL29196173 | 0.98 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL3875750 | 0.92 | — | — | |
| SCHEMBL7971596 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL5555196 | 0.90 | LCK (0.56) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1449604 | 0.89 | LCK (0.73) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |