SCHEMBL28464800

SCHEMBL28464800

c1coc(-c2ccoc2-c2ccoc2-c2nccs2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.40
MYC P01106 1/20 0.40
PDPK1 O15530 1/20 0.39
ALDH1A1 P00352 8/20 0.38
KDM4E B2RXH2 5/20 0.38
HSD17B10 Q99714 5/20 0.38
MAPT P10636 4/20 0.38
RAB9A P51151 3/20 0.38
PKM P14618 2/20 0.38
GFER P55789 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
ADORA2A P29274 2/20 0.37
ADORA1 P30542 2/20 0.37
ADRB2 P07550 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.35
CYP2A6 P11509 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2E1 P05181 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5349589 0.80 MYC (0.49) CYP19A1MYCPDPK1ALDH1A1KDM4E
SCHEMBL30375147 0.76 ALDH1A1 (0.41) ALDH1A1KDM4EHSD17B10MAPTRAB9A
SCHEMBL29695129 0.72 ALDH1A1 (0.44) ALDH1A1KDM4EHSD17B10MAPTRAB9A
SCHEMBL28636603 0.71 MYC (0.44) CYP19A1MYCPDPK1ALDH1A1KDM4E
SCHEMBL27676701 0.70 MYC (0.42) CYP19A1MYCPDPK1ALDH1A1KDM4E
SCHEMBL5026233 0.70 ADORA2A (0.53) CYP19A1MYCALDH1A1KDM4EHSD17B10
SCHEMBL6252959 0.69 ADORA1 (0.69) ALDH1A1KDM4EHSD17B10MAPTADORA2A
SCHEMBL5016124 0.69 ADORA2A (0.50) CYP19A1MYCALDH1A1KDM4EHSD17B10
SCHEMBL5016068 0.69 ADORA2A (0.50) CYP19A1MYCALDH1A1KDM4EHSD17B10
SCHEMBL5016171 0.66 ADORA2A (0.60) CYP19A1MYCKDM4EADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111728183-A Plum essence and beverage containing same 广州和泉食品有限公司 2020-10-02 CN disclosed