Oleic Acid

Oleic Acid

SCHEMBL28465415

CC(C)O.CCCCCCCC/C=C\CCCCCCCC(=O)O.CCO.NC(N)=O.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Ca+2].[Ca+2].[Ca+2]

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BHRH2IMPA1

The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.51
PPARD Q03181 5/20 0.51
PPARA Q07869 5/20 0.51
F7 P08709 5/20 0.51
F3 P13726 5/20 0.51
TERT O14746 3/20 0.51
PTPN1 P18031 3/20 0.51
HSD17B10 Q99714 3/20 0.51
FABP4 P15090 3/20 0.51
MAPT P10636 2/20 0.51
BLM P54132 2/20 0.51
LMNA P02545 2/20 0.51
ALOX15 P16050 2/20 0.51
DUSP3 P51452 2/20 0.51
CYP19A1 P11511 2/20 0.51
PTGS1 P23219 2/20 0.51
NR4A2 P43354 2/20 0.51
SIRT6 Q8N6T7 2/20 0.51
PTPN7 P35236 2/20 0.51
TDP1 Q9NUW8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL11127113 0.79 GPR84 (0.57) PPARGPPARDPPARAPTPN1HSD17B10
Oleic Acid SCHEMBL21647155 0.78 PPARG (0.85) PPARGPPARDPPARAF7F3
Elaidic Acid SCHEMBL31146551 0.76 PPARG (0.82) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL28413435 0.76 PPARG (0.82) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL29398120 0.76 PPARG (0.82) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL1976059 0.76 PPARG (0.82) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL9276223 0.76 PPARG (0.89) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL9276214 0.76 PPARG (0.89) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL11115452 0.75 PPARG (0.70) PPARGPPARDPPARAF7F3
Oleic Acid SCHEMBL5874354 0.75 PPARG (0.79) PPARGPPARDPPARAF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111819947-B Germination accelerating method beneficial to dormancy breaking of sorbus tianshanensis seeds 新疆农业大学 2022-03-04 CN claimed
CN-111819947-A Germination accelerating method beneficial to dormancy breaking of sorbus tianshanensis seeds 新疆林业科学院 2020-10-27 CN claimed
CN-111819947-B Germination accelerating method beneficial to dormancy breaking of sorbus tianshanensis seeds 新疆农业大学 2022-03-04 CN disclosed
CN-111819947-A Germination accelerating method beneficial to dormancy breaking of sorbus tianshanensis seeds 新疆林业科学院 2020-10-27 CN disclosed