Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556778 | 0.88 | MAPT (0.43) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL1869807 | 0.88 | MAPT (0.45) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL22556898 | 0.85 | MAPT (0.39) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL7260647 | 0.85 | MAPT (0.42) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL1870418 | 0.85 | MAPT (0.42) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL28466380 | 0.83 | GRM5 (0.47) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL7256007 | 0.83 | MAPT (0.41) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL22579417 | 0.83 | NR1H2 (0.44) | MAPTSMN1; SMN2GRM5ESR2NR1H2 | |
| SCHEMBL29716002 | 0.83 | CASP3 (0.51) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL1866955 | 0.83 | MAPT (0.45) | MAPTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825654-A | Phenylmethylene piperidine derivatives, preparation method, intermediates and uses thereof | 北京酷瓴生物技术有限公司 | 2020-10-27 | — | — | CN | disclosed |