Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | RB1 | P06400 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428079 | 0.93 | HSD17B10 (0.50) | MEN1KMT2AHSD17B10BRD3KDM4E | |
| SCHEMBL28459559 | 0.90 | MEN1 (0.45) | MEN1KMT2AHSD17B10BRD3KDM4E | |
| SCHEMBL28459535 | 0.90 | MEN1 (0.45) | MEN1KMT2AHSD17B10BRD3KDM4E | |
| SCHEMBL1919190 | 0.83 | HTR2A (0.46) | MEN1KMT2AHSD17B10BRD3KDM4E | |
| SCHEMBL15101404 | 0.74 | KDM4E (0.54) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL296017 | 0.71 | HSD17B10 (0.48) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL224482 | 0.70 | MEN1 (0.47) | MEN1KMT2AHSD17B10BRD3KDM4E | |
| SCHEMBL2307927 | 0.69 | HTR2A (0.43) | MEN1KMT2AHSD17B10BRD3KDM4E | |
| SCHEMBL481360 | 0.66 | KDM4E (0.68) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL29936982 | 0.66 | KDM4E (0.68) | MEN1KMT2AHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747981-A | Transition metal compound and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111747981-A | Transition metal compound and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-10-09 | — | — | CN | disclosed |