Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 16/20 | 0.66 |
| ▸ | JAK1 | P23458 | 16/20 | 0.66 |
| ▸ | JAK3 | P52333 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472073 | 0.91 | JAK1 (0.67) | JAK2JAK1JAK3 | |
| SCHEMBL28462194 | 0.90 | JAK2 (0.66) | JAK2JAK1JAK3 | |
| SCHEMBL28468665 | 0.87 | JAK2 (0.58) | JAK2JAK1JAK3 | |
| SCHEMBL28461972 | 0.86 | JAK2 (0.57) | JAK2JAK1JAK3 | |
| SCHEMBL3377812 | 0.86 | JAK2 (0.57) | JAK2JAK1JAK3 | |
| SCHEMBL18522662 | 0.86 | JAK2 (0.54) | JAK2JAK1JAK3 | |
| SCHEMBL28464766 | 0.85 | JAK2 (0.51) | JAK2JAK1JAK3 | |
| SCHEMBL3376133 | 0.85 | JAK2 (0.56) | JAK2JAK1JAK3 | |
| SCHEMBL22462090 | 0.85 | JAK2 (0.65) | JAK2JAK1 | |
| SCHEMBL28462188 | 0.85 | JAK2 (0.58) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620873-B | Pyrrolo [2,3-d ] pyrimidine derivatives containing piperidine and preparation and application thereof | 沈阳药科大学 | 2021-12-28 | — | — | CN | claimed |
| CN-111620873-A | Pyrrolo [2,3-d ] pyrimidine derivatives containing piperidine and preparation and application thereof | 沈阳药科大学 | 2020-09-04 | — | — | CN | claimed |
| CN-111620873-B | Pyrrolo [2,3-d ] pyrimidine derivatives containing piperidine and preparation and application thereof | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-111620873-A | Pyrrolo [2,3-d ] pyrimidine derivatives containing piperidine and preparation and application thereof | 沈阳药科大学 | 2020-09-04 | — | — | CN | disclosed |