Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22462089 | 0.92 | JAK1 (0.66) | JAK2JAK1 | |
| SCHEMBL22462086 | 0.90 | JAK2 (0.66) | JAK2JAK1 | |
| SCHEMBL14563734 | 0.87 | JAK2 (0.52) | JAK2JAK1 | |
| SCHEMBL27182358 | 0.86 | JAK2 (0.51) | JAK2JAK1 | |
| SCHEMBL14563805 | 0.85 | JAK2 (0.65) | JAK2JAK1 | |
| SCHEMBL14563845 | 0.85 | JAK2 (0.50) | JAK2JAK1 | |
| SCHEMBL28466379 | 0.85 | JAK2 (0.66) | JAK2JAK1 | |
| SCHEMBL14563676 | 0.85 | JAK2 (0.69) | JAK2JAK1 | |
| SCHEMBL14563857 | 0.84 | JAK2 (0.53) | JAK2JAK1 | |
| SCHEMBL17387434 | 0.81 | JAK2 (0.65) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715347-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2020-09-30 | — | — | EP | claimed |
| EP-3715347-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2020-09-30 | — | — | EP | disclosed |