Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 9/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846676 | 1.00 | PRMT1 (0.47) | PRMT1BLMMLNRNR1I2PGR | |
| SCHEMBL2846007 | 0.84 | PRMT1 (0.49) | PRMT1BLMMLNRNR1I2PGR | |
| SCHEMBL2846009 | 0.84 | PRMT1 (0.49) | PRMT1BLMMLNRNR1I2PGR | |
| SCHEMBL15178538 | 0.79 | PRMT1 (0.41) | PRMT1BLMMLNRNR1I2PGR | |
| SCHEMBL12156973 | 0.77 | PRMT1 (0.44) | PRMT1BLMMLNRNR1I2PGR | |
| SCHEMBL14596157 | 0.76 | PRMT1 (0.58) | PRMT1BLMMLNRNR1I2PGR | |
| SCHEMBL18103640 | 0.76 | PRMT1 (0.58) | PRMT1BLMMLNRNR1I2PGR | |
| SCHEMBL7701839 | 0.74 | ABCG2 (0.32) | PRMT1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL3468060 | 0.73 | MAPT (0.45) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL3468065 | 0.73 | MAPT (0.45) | MEN1KMT2APOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129293-A1 | Near Infrared Imaging Agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2010-05-27 | — | — | US | disclosed |
| US-7655217-B2 | Near infrared imaging agent | Institut fur Diagnosikforschung GmbH (DE) | 2010-02-02 | — | — | US | disclosed |
| US-7445767-B2 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20060165599-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| US-20060165598-A1 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2006-07-27 | — | — | US | disclosed |
| US-7025949-B2 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2006-04-11 | — | — | US | disclosed |
| US-6926885-B2 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2005-08-09 | — | — | US | disclosed |
| US-20050169844-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-08-04 | — | — | US | disclosed |
| US-6913743-B2 | As contrast medium for fluorescence and transillumination diagnostics; drugs | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-07-05 | — | — | US | disclosed |
| US-20050106106-A1 | In-vivo diagnostic method by near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN (DE) | 2005-05-19 | — | — | US | disclosed |
| US-20030170179-A1 | Near infrared imaging agent | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITA (COPY) | 2003-09-11 | — | — | US | disclosed |
| US-20030026763-A1 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN | 2003-02-06 | — | — | US | disclosed |
| EP-1181940-A2 | In vivo diagnostics by near infrared radiation | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 2002-02-27 | — | — | EP | disclosed |
| US-20010055567-A1 | In-vivo diagnostic method by means of near infrared radiation | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH AN DER FREIEN UNIVERSITAT BERLIN | 2001-12-27 | — | — | US | disclosed |
| US-6258340-B1 | USING WATER-SOLUBLE DYES AND THEIR BIOMOLECULE ADDUCTS EACH HAVING SPECIFIC PHOTOPHYSICAL AND PHARMOCHEMICAL PROPERTIES | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| US-6083485-A | USEING WATER-SOLUBLE DYES AND THEIR BIOMOLECULE ADDUCTS AS CONTRAST MEDIUM FOR FLUORESCENCE AND TRANSILLUMINATION DIAGNOSTICS IN THE NEAR INFRARED RADIATION RANGE | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2000-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165598-A1 | In-vivo diagnostic method by near infrared radiation | GUSB, CYBA, ABCG2 | PRMT1 2769/4885BLM 628/4885MLNR 1519/4885 |
| US-20100129293-A1 | Near Infrared Imaging Agent | UGT1A10, ABCG2, SLCO1B1 | PRMT1 2675/4885BLM 1226/4885MLNR 723/4885 |
| US-20050106106-A1 | In-vivo diagnostic method by near infrared radiation | GUSB, CYBA, ABCG2 | PRMT1 2769/4885BLM 628/4885MLNR 1519/4885 |
| US-20050169844-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | PRMT1 2675/4885BLM 1226/4885MLNR 723/4885 |
| US-20060165599-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | PRMT1 2675/4885BLM 1226/4885MLNR 723/4885 |
| US-20010055567-A1 | In-vivo diagnostic method by means of near infrared radiation | GUSB, ABCG2, SLCO1B1 | PRMT1 3243/4885BLM 767/4885MLNR 1140/4885 |
| US-20030026763-A1 | In-vivo diagnostic method by means of near infrared radiation | GUSB, ABCG2, SLCO1B1 | PRMT1 3243/4885BLM 767/4885MLNR 1140/4885 |
| US-20030170179-A1 | Near infrared imaging agent | UGT1A10, ABCG2, SLCO1B1 | PRMT1 2675/4885BLM 1226/4885MLNR 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.