Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405154 | 0.80 | USP2 (0.40) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL7405157 | 0.80 | USP2 (0.40) | NR1H2USP2SMN1; SMN2ESR2ADORA1 | |
| SCHEMBL25422301 | 0.80 | USP2 (0.47) | NR1H2USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14800964 | 0.74 | USP2 (0.52) | NR1H2USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18294 | 0.73 | USP2 (0.69) | NR1H2USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL698803 | 0.73 | USP2 (0.69) | NR1H2USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21876055 | 0.73 | USP2 (0.50) | NR1H2USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1968373 | 0.72 | USP2 (0.46) | NR1H2USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13244889 | 0.72 | USP2 (0.46) | NR1H2USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3243997 | 0.72 | USP2 (0.44) | NR1H2USP2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107174584-B | Application of piperazine structure-containing compound in preparation of LSD1 inhibitor | 福建金乐医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |