SCHEMBL698803

SCHEMBL698803

CC(C)(C)OC(=O)N1CC1

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
HPGD P15428 1/20 0.56
EPHX2 P34913 1/20 0.54
RECQL P46063 1/20 0.53
EPHX1 P07099 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
ALDH1A1 P00352 2/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
POLB P06746 1/20 0.49
HTT P42858 1/20 0.49
ATM Q13315 1/20 0.49
GPR119 Q8TDV5 1/20 0.49
NR1H2 P55055 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18294 1.00 USP2 (0.69) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL27388627 0.93 USP2 (0.62) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL16612394 0.93 USP2 (0.62) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL2223924 0.91 USP2 (0.60) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL6061822 0.91 USP2 (0.60) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL2915295 0.91 USP2 (0.60) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL2430769 0.91 USP2 (0.60) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL8874348 0.91 USP2 (0.60) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL17344112 0.91 USP2 (0.60) USP2SMN1; SMN2HPGDEPHX2RECQL
SCHEMBL334091 0.91 USP2 (0.60) USP2SMN1; SMN2HPGDEPHX2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517998-B Zwitterionic surfactant and preparation method thereof 杨凌单色生物科技有限公司 2022-04-22 CN claimed
CN-111517993-B Zwitterionic fluorocarbon surfactant and preparation method thereof 杨凌单色生物科技有限公司 2022-04-22 CN claimed
CN-111389305-B Amphoteric ion organic silicon surfactant and preparation method thereof 杨凌单色生物科技有限公司 2021-09-07 CN claimed
CN-111517993-A Zwitterionic fluorocarbon surfactant and preparation method thereof 杨凌单色生物科技有限公司 2020-08-11 CN claimed
CN-111517998-A Zwitterionic surfactant and preparation method thereof 杨凌单色生物科技有限公司 2020-08-11 CN claimed
CN-111389305-A Amphoteric ion organic silicon surfactant and preparation method thereof 杨凌单色生物科技有限公司 2020-07-10 CN claimed
EP-1794129-B1 Synthesis by chiral diamine-mediated asymmetric alkylation JANSSEN PHARMACEUTICA NV (BE) 2015-12-30 EP claimed
EP-1794129-A4 SYNTHESIS BY CHIRAL DIAMINE-MEDIATED ASYMMETRIC ALKYLATION JANSSEN PHARMACEUTICA NV (BE) 2009-09-02 EP claimed
US-7402670-B2 Synthesis by chiral diamine-mediated asymmetric alkylation JANSSEN PHARMACEUTICA, N.V. (BE) 2008-07-22 US claimed
EP-1794129-A2 SYNTHESIS BY CHIRAL DIAMINE-MEDIATED ASYMMETRIC ALKYLATION JANSSEN PHARMACEUTICA N.V. (BE) 2007-06-13 EP claimed
WO-2006039383-A2 SYNTHESIS BY CHIRAL DIAMINE-MEDIATED ASYMMETRIC ALKYLATION JANSSEN PHARMACEUTICA N.V. (BE) 2006-04-13 WO claimed
US-20060069250-A1 Synthesis by chiral diamine-mediated asymmetric alkylation DENG XIAOHU 2006-03-30 US claimed
EP-0595924-B1 PLATELET ACTIVATING FACTOR ANTAGONISTS ABBOTT LAB (US) 1999-04-14 EP claimed
EP-0350131-A2 New 1,4-diazepine derivatives having anti-ulcer activity DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1990-01-10 EP claimed
EP-4396305-B1 SYNTHESIS OF MDMA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDMA ISOMERS EMPATHBIO INC (US) 2026-05-06 EP disclosed
US-12492178-B2 Stable polymorph of R-MDMA HCl EMPATHBIO, INC. (US) 2025-12-09 US disclosed
EP-4615828-A2 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EmpathBio, Inc. (US) 2025-09-17 EP disclosed
US-5140024-A Thienofuro- or thienodiazepines and pyridofuro- or thienodizsepines; antisecretory and -inflammatory agents; gastrointestinal disorders DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1992-08-18 US disclosed
US-4985423-A New 1,4-diazepine derivatives having anit-ulcer activity DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1991-01-15 US disclosed
EP-0350131-A2 New 1,4-diazepine derivatives having anti-ulcer activity DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060069250-A1 Synthesis by chiral diamine-mediated asymmetric alkylation SRM, SMOX, DDC USP2 1919/4885SMN1; SMN2 3550/4885HPGD 2209/4885
US-12492178-B2 Stable polymorph of R-MDMA HCl HTR3A, OPRM1, HTR3B USP2 2466/4885SMN1; SMN2 1250/4885HPGD 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.