Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28473469 | 0.80 | CDK4 (0.32) | — | |
| Methane SCHEMBL28575123 | 0.77 | NUAK1 (0.43) | — | |
| Methane SCHEMBL5900460 | 0.74 | CDK4 (0.34) | — | |
| Methane SCHEMBL28462333 | 0.73 | CCNE1 (0.31) | — | |
| Methane SCHEMBL4826066 | 0.73 | CCND1 (0.49) | — | |
| Methane SCHEMBL28475491 | 0.73 | CCNE1 (0.31) | — | |
| Methane SCHEMBL4833118 | 0.72 | CCND1 (0.41) | — | |
| Methane SCHEMBL5900481 | 0.71 | CCND1 (0.33) | — | |
| Methane SCHEMBL5900369 | 0.71 | CCNE1 (0.37) | — | |
| Methane SCHEMBL4875868 | 0.70 | CCND1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191857-B | 6-substituted pyrido [2,3-D ] pyrimidines as protein kinase inhibitors | 晟科药业（江苏）有限公司 | 2020-10-23 | — | — | CN | disclosed |