SCHEMBL28467404

SCHEMBL28467404

CCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)OCC

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.82
CYP3A4 P08684 2/20 0.82
ALOX15 P16050 2/20 0.82
TSHR P16473 2/20 0.82
HSD17B10 Q99714 2/20 0.82
TDP1 Q9NUW8 2/20 0.82
NR1I2 O75469 1/20 0.71
PGR P06401 1/20 0.71
ADORA3 P0DMS8 1/20 0.71
PTGS2 P35354 1/20 0.71
PDE4D Q08499 1/20 0.71
MGLL Q99685 1/20 0.59
MAPT P10636 1/20 0.57
THRB P10828 1/20 0.57
CNR1 P21554 1/20 0.57
KDM4E B2RXH2 3/20 0.56
F7 P08709 3/20 0.56
F3 P13726 3/20 0.56
PPARG P37231 2/20 0.56
PPARD Q03181 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28304049 1.00 ALDH1A1 (0.82) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL29597391 1.00 ALDH1A1 (0.82) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL21670442 0.98 ALDH1A1 (0.79) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL21670441 0.98 ALDH1A1 (0.79) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL29141243 0.97 ALDH1A1 (0.77) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL28116049 0.95 HSD17B10 (0.73) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL31515053 0.95 HSD17B10 (0.73) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
Ethyl Linoleate SCHEMBL15469171 0.93 ALDH1A1 (0.82) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL6808235 0.93 ALDH1A1 (0.82) ALDH1A1CYP3A4ALOX15TSHRHSD17B10
SCHEMBL6808635 0.93 ALDH1A1 (0.82) ALDH1A1CYP3A4ALOX15TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12440466-B2 Fatty acid derivatives for treating non-alcoholic steatohepatitis BASF AS (NO) 2025-10-14 US disclosed
EP-3720431-B1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-10-30 EP disclosed
US-20240156769-A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-05-16 US disclosed
US-11925614-B2 Fatty acid derivatives for treating non-alcoholic steatohepatitis BASF AS (NO) 2024-03-12 US disclosed
CN-111712240-A Fatty acid derivatives for the treatment of non-alcoholic steatohepatitis 巴斯夫股份公司 2020-09-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240156769-A1 FATTY ACID DERIVATIVES FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS CPT1A, NR1H2, NR1H3 ALDH1A1 154/4885CYP3A4 772/4885ALOX15 66/4885
US-12440466-B2 Fatty acid derivatives for treating non-alcoholic steatohepatitis CPT1A, NR1H2, NR1H3 ALDH1A1 154/4885CYP3A4 772/4885ALOX15 66/4885
US-11925614-B2 Fatty acid derivatives for treating non-alcoholic steatohepatitis CPT1A, NR1H3, NR1H2 ALDH1A1 162/4885CYP3A4 796/4885ALOX15 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.