Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.67 |
| ▸ | IGF1R | P08069 | 4/20 | 0.67 |
| ▸ | INSR | P06213 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942052 | 1.00 | EGFR (0.67) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL28942091 | 0.95 | EGFR (0.69) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL28471867 | 0.95 | EGFR (0.69) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL14719556 | 0.94 | EGFR (0.77) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL28942092 | 0.93 | EGFR (0.62) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL14719359 | 0.89 | EGFR (0.78) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL28942027 | 0.88 | EGFR (0.60) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL28461533 | 0.88 | EGFR (0.70) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL28942037 | 0.88 | EGFR (0.70) | EGFRKCNH2IGF1RINSR | |
| SCHEMBL28942132 | 0.88 | EGFR (0.71) | EGFRKCNH2IGF1RINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191861-B | N- [5- (pyrimidin-2-amino) -2, 4-disubstituted-phenyl ] -trans-2, 4-pentadiene-amide | 天津大学 | 2020-10-02 | — | — | CN | disclosed |