Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | KDM6B | O15054 | 1/20 | 0.55 |
| ▸ | KDM4A | O75164 | 1/20 | 0.55 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthranilic Acid SCHEMBL28159523 | 0.98 | KDM4E (0.53) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Aminobenzoic Acid SCHEMBL28218510 | 0.88 | MAPT (0.46) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Anthranilic Acid SCHEMBL3322707 | 0.88 | MAPT (0.52) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Anthranilic Acid SCHEMBL27738855 | 0.87 | MAPT (0.59) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Anthranilic Acid SCHEMBL9353404 | 0.87 | MAPT (0.59) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Anthranilic Acid SCHEMBL2953168 | 0.87 | ALDH1A1 (0.65) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Anthranilic Acid SCHEMBL29802554 | 0.87 | ALDH1A1 (0.65) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Anthranilic Acid SCHEMBL2961107 | 0.87 | ALDH1A1 (0.65) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Anthranilic Acid SCHEMBL362171 | 0.87 | ALDH1A1 (0.65) | KDM4EMAPTALDH1A1KMT2ATDP1 | |
| Anthranilic Acid SCHEMBL29365173 | 0.87 | ALDH1A1 (0.65) | KDM4EMAPTALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108033964-B | Pyridyl imidazobenzodiazepine propionate compound and synthesis and application thereof | 杭州奥默医药股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-112142746-A | Benzodiazepine compound, preparation method and medical application thereof | 四川大学华西医院 | 2020-12-29 | — | — | CN | claimed |
| CN-111727190-A | Pyridyl imidazobenzodiazepine propionate compound and synthesis and application thereof | 杭州奥默医药股份有限公司 | 2020-09-29 | — | — | CN | claimed |
| CN-112142746-B | Benzodiazepine compound, preparation method and medical application thereof | 四川大学华西医院 | 2021-09-24 | — | — | CN | disclosed |
| CN-108033964-B | Pyridyl imidazobenzodiazepine propionate compound and synthesis and application thereof | 杭州奥默医药股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112142746-A | Benzodiazepine compound, preparation method and medical application thereof | 四川大学华西医院 | 2020-12-29 | — | — | CN | disclosed |
| CN-111727190-A | Pyridyl imidazobenzodiazepine propionate compound and synthesis and application thereof | 杭州奥默医药股份有限公司 | 2020-09-29 | — | — | CN | disclosed |