SCHEMBL28468474

SCHEMBL28468474

CCCCCCCC(=O)c1ccccc1C#N

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
ALDH1A1 P00352 3/20 0.47
HTT P42858 2/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
HSD17B3 P37058 6/20 0.45
CES2 O00748 2/20 0.44
LMNA P02545 1/20 0.44
CES1 P23141 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HPGD P15428 1/20 0.42
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10597212 1.00 TSHR (0.51) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL28464696 1.00 TSHR (0.51) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL8462996 0.94 TSHR (0.57) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL30350086 0.94 TSHR (0.57) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL10787348 0.86 ALDH1A1 (0.49) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL11069839 0.86 ALDH1A1 (0.49) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL7999608 0.86 ALDH1A1 (0.49) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL2356747 0.86 ALDH1A1 (0.49) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL20503857 0.85 HTT (0.47) TSHRALDH1A1HTTMEN1MAPT
SCHEMBL21582020 0.85 ALDH1A1 (0.47) TSHRALDH1A1HTTMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111868042-A Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentyl carboxylic acid derivatives 拜耳公司 2020-10-30 CN disclosed
CN-111629592-A Liquid fertilizer dispersion composition and method thereof 拜耳作物科学有限合伙公司 2020-09-04 CN disclosed