Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 13/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 13/20 | 0.41 |
| ▸ | GLMN | Q92990 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849696 | 0.80 | DPP4 (0.45) | DPP8DPP9DPP4FAP | |
| SCHEMBL2846106 | 0.69 | DPP4 (0.46) | DPP8DPP9DPP4FAP | |
| SCHEMBL15009296 | 0.68 | EPHX2 (0.47) | EPHX2 | |
| SCHEMBL2849630 | 0.63 | PREP (0.52) | DPP8DPP9GLMNDPP4FAP | |
| SCHEMBL2848405 | 0.63 | DPP8 (0.47) | DPP8DPP9GLMNDPP4FAP | |
| SCHEMBL2851493 | 0.63 | PREP (0.49) | DPP8DPP9DPP4FAP | |
| Hydrochloric Acid SCHEMBL2841474 | 0.62 | PREP (0.49) | DPP8DPP9DPP4FAP | |
| SCHEMBL2843589 | 0.61 | DPP4 (0.56) | DPP8DPP9DPP4FAP | |
| SCHEMBL2844697 | 0.61 | PREP (0.46) | DPP8DPP9GLMNDPP4FAP | |
| SCHEMBL301874 | 0.61 | FAP (0.47) | DPP8DPP9DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160328-A1 | NEW COMPOUNDS USEFUL FOR DPP-IV ENZYME INHIBITION | SANOFI-AVENTIS (FR) | 2010-06-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160328-A1 | NEW COMPOUNDS USEFUL FOR DPP-IV ENZYME INHIBITION | DPP4, DPP7, DPP9 | DPP8 5/4885DPP9 3/4885GLMN 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.