SCHEMBL28469110

SCHEMBL28469110

COc1cccc2cc(C(=O)OC(C)(C)C)c(=O)oc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.70
CA1 P00915 2/20 0.70
CA2 P00918 2/20 0.70
CA9 Q16790 2/20 0.70
CA3 P07451 1/20 0.70
CA4 P22748 1/20 0.70
CA6 P23280 1/20 0.70
CA5A P35218 1/20 0.70
CA7 P43166 1/20 0.70
CA14 Q9ULX7 1/20 0.70
CA5B Q9Y2D0 1/20 0.70
POLB P06746 4/20 0.68
HSD17B10 Q99714 2/20 0.65
KMT2A Q03164 3/20 0.64
MEN1 O00255 2/20 0.64
ALDH1A1 P00352 5/20 0.61
MAPT P10636 4/20 0.61
KDM4E B2RXH2 2/20 0.57
HPGD P15428 4/20 0.56
RAB9A P51151 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28445182 0.87 CA12 (0.77) CA12CA1CA2CA9CA3
SCHEMBL22129769 0.84 CNR2 (0.49) CA12CA1CA2CA9CA3
SCHEMBL980310 0.82 CA12 (1.00) CA12CA1CA2CA9CA3
SCHEMBL7519005 0.82 CA12 (0.79) CA12CA1CA2CA9CA3
SCHEMBL2031480 0.82 KMT2A (0.74) CA12CA1CA2CA9CA3
SCHEMBL11339310 0.81 CA12 (0.77) CA12CA1CA2CA9CA3
Hydrochloric Acid SCHEMBL11339314 0.81 CA12 (0.97) CA12CA1CA2CA9CA3
SCHEMBL11495843 0.81 CA12 (0.77) CA12CA1CA2CA9CA3
SCHEMBL31619161 0.81 CA12 (0.71) CA12CA1CA2CA9CA3
SCHEMBL2034208 0.78 CA12 (0.76) CA12CA1CA2CA9CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111411137-B Method for synthesizing 8-methoxyl coumarin-3-carboxylic acid-6' -O-D-glucose ester on line under catalysis of lipase 浙江农林大学 2023-04-25 CN disclosed
CN-111411137-A Method for synthesizing 8-methoxycoumarin-3-carboxylic acid-6' -O-D-glucose ester on line under catalysis of lipase 浙江农林大学 2020-07-14 CN disclosed