Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 1.00 |
| ▸ | CA1 | P00915 | 1/20 | 1.00 |
| ▸ | CA2 | P00918 | 1/20 | 1.00 |
| ▸ | CA3 | P07451 | 1/20 | 1.00 |
| ▸ | CA4 | P22748 | 1/20 | 1.00 |
| ▸ | CA6 | P23280 | 1/20 | 1.00 |
| ▸ | CA5A | P35218 | 1/20 | 1.00 |
| ▸ | CA7 | P43166 | 1/20 | 1.00 |
| ▸ | CA9 | Q16790 | 1/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11339314 | 0.99 | CA12 (0.97) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7519005 | 0.88 | CA12 (0.79) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11347549 | 0.87 | CA12 (0.77) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11495843 | 0.87 | CA12 (0.77) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11339310 | 0.87 | CA12 (0.77) | CA12CA1CA2CA3CA4 | |
| SCHEMBL28445182 | 0.87 | CA12 (0.77) | CA12CA1CA2CA3CA4 | |
| SCHEMBL2034208 | 0.86 | CA12 (0.76) | CA12CA1CA2CA3CA4 | |
| SCHEMBL22041596 | 0.85 | CA12 (0.73) | CA12CA1CA2CA3CA4 | |
| SCHEMBL28155268 | 0.85 | CA12 (0.74) | CA12CA1CA2CA3CA4 | |
| SCHEMBL981636 | 0.85 | CA12 (0.73) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8968711-B2 | Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process | L'OREAL (FR) | 2015-03-03 | — | — | US | claimed |
| CN-103965268-A | Preparation method and application of 8-methoxycoumarin-3-glucose ester formate | HEBEI CHINA TOBACCO INDUSTRY CO LTD | 2014-08-06 | — | — | CN | claimed |
| US-20100272660-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT | L'OREAL (FR) | 2010-10-28 | — | — | US | claimed |
| US-20100239509-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS | L'OREAL (FR) | 2010-09-23 | — | — | US | claimed |
| US-4196128-A | Process for the preparation of 3-cyanochromones | WARNER-LAMBERT COMPANY (US) | 1980-04-01 | — | — | US | claimed |
| CN-119192113-A | Pleuromutilin derivative and preparation method and application thereof | 西华大学 | 2024-12-27 | — | — | CN | disclosed |
| WO-2023204123-A1 | COMPOUND, ACID GENERATOR COMPRISING SAID COMPOUND, PHOTORESIST, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE USING SAID PHOTORESIST | サンアプロ株式会社 | 2023-10-26 | — | — | WO | disclosed |
| CN-111411137-B | Method for synthesizing 8-methoxyl coumarin-3-carboxylic acid-6' -O-D-glucose ester on line under catalysis of lipase | 浙江农林大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-112939916-B | Method for synthesizing coumarin-3-carboxylic acid compounds by one-pot two-step method | 河南中烟工业有限责任公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-110804045-B | Coumarin hybrid pyridone amide derivative with potential anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-113024499-A | Green synthesis method of coumarin-3-carboxylic acid compounds | 河南中烟工业有限责任公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-112939916-A | Method for synthesizing coumarin-3-carboxylic acid compounds by one-pot two-step method | 河南中烟工业有限责任公司 | 2021-06-11 | — | — | CN | disclosed |
| US-20100239509-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS | L'OREAL (FR) | 2010-09-23 | — | — | US | disclosed |
| WO-2009089508-A1 | ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-07-16 | — | — | WO | disclosed |
| US-20090028807-A1 | COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION | L'OREAL (FR) | 2009-01-29 | — | — | US | disclosed |
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |
| EP-0988298-A1 | COUMARIN DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998055472-A1 | COUMARIN DERIVATIVES, METHODS OF PREPARATION AND APPLICATION AS MEDICINES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-12-10 | — | — | WO | disclosed |
| US-4303664-A | Novel penicillin derivatives containing a coumarin nucleus and medicines containing the same | TEIJIN LIMITED (JP) | 1981-12-01 | — | — | US | disclosed |
| US-4196128-A | Process for the preparation of 3-cyanochromones | WARNER-LAMBERT COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239509-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS | CUTA, SUCLG1, KRT18 | CA12 15/4885CA1 185/4885CA2 214/4885 |
| US-20090028807-A1 | COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION | CUTA, SYMPK, TPRKB | CA12 3507/4885CA1 4550/4885CA2 3819/4885 |
| US-20100272660-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT | ACMSD, CUTA, PCCA | CA12 403/4885CA1 1334/4885CA2 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.