Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL14742787 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL28200262 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28275631 | 1.00 | — | — | |
| Bicarbonate SCHEMBL787477 | 1.00 | — | — | |
| Bicarbonate SCHEMBL14562616 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28490163 | 0.94 | — | — | |
| Bicarbonate SCHEMBL27869306 | 0.94 | — | — | |
| Bicarbonate SCHEMBL3336735 | 0.94 | — | — | |
| Bicarbonate SCHEMBL14578980 | 0.94 | — | — | |
| Bicarbonate SCHEMBL28232617 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013739-B1 | NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE | WELLA GERMANY GMBH (DE) | 2024-10-02 | — | — | EP | claimed |
| US-20220298101-A1 | NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE | WELLA GERMANY GMBH (DE) | 2022-09-22 | — | — | US | claimed |
| EP-4013739-A1 | NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE | Wella Germany GmbH (DE) | 2022-06-22 | — | — | EP | claimed |
| WO-2021028506-A1 | NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE | COTY INC. (US) | 2021-02-18 | — | — | WO | claimed |
| CN-109746999-A | A kind of wood fire retardant | 丹阳市博元安全生产服务有限公司 | 2019-05-14 | — | — | CN | claimed |
| CN-109731450-A | A kind of two-part flue gas aftertreatment technology | 北京利德衡环保工程有限公司 | 2019-05-10 | — | — | CN | claimed |
| CN-104924390-A | Wood fire retardant | ZHANG PING | 2015-09-23 | — | — | CN | claimed |
| CN-104478267-A | Calcium carbonate and sodium carbonate complexing agent and preparation method thereof | YIXING TIANLI CHEMICAL NANO TECHNOLOGY CO LTD | 2015-04-01 | — | — | CN | claimed |
| WO-2024258616-A2 | VAPOR PERMEABLE, WATER RESISTIVE, AND FIRE RESISTIVE ARTICLES | HEXION INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| US-20240417971-A1 | VAPOR PERMEABLE, WATER RESISTIVE, AND FIRE RESISTIVE ARTICLES | HEXION INC. | 2024-12-19 | — | — | US | disclosed |
| WO-2024258614-A2 | POLE CAPS AND POLE PROTECTION SYSTEMS | HEXION INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| US-20240417993-A1 | POLE CAPS AND POLE PROTECTION SYSTEMS | HEXION INC. | 2024-12-19 | — | — | US | disclosed |
| WO-2023230011-A1 | FIRE-RESISTANT COMPOSITIONS | HEXION INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| US-20230374319-A1 | FIRE-RESISTANT COMPOSITIONS | HEXION INC. | 2023-11-23 | — | — | US | disclosed |
| CN-1784223-A | Use of phenoxyacetic acid derivatives for treating hyperactive bladder | KISSEI PHARMACEUTICAL (JP) | 2006-06-07 | — | — | CN | disclosed |
| CN-1658767-A | Compositions for modulating physiological responses or inducing immune responses | PEROS SYSTEMES TECHNOLOGIES IN (CA) | 2005-08-24 | — | — | CN | disclosed |
| CN-1406112-A | Composition for intestinal delivery | AQUA SOLUTION INC (CA) | 2003-03-26 | — | — | CN | disclosed |
| US-6086998-A | Non-inflammable fiber product | PROTEKUM UMWELTINSTITUT GMBH ORANIENBURG (DE) | 2000-07-11 | — | — | US | disclosed |
| US-4440779-A | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO., INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0068460-A1 | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298101-A1 | NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE | PNMT, TYR, DDT | CA1 4858/4885CA2 4270/4885CA9 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.