Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 10/20 | 0.51 |
| ▸ | CCND1 | P24385 | 10/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28466160 | 0.77 | CDK4 (0.46) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL23945224 | 0.76 | CDK4 (0.71) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL28466222 | 0.75 | CDK4 (0.41) | CDK4CCND1DHODH | |
| SCHEMBL28465176 | 0.74 | CDK4 (0.50) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL20227597 | 0.72 | KDM4E (0.44) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL23668299 | 0.72 | CDK4 (0.47) | CDK4CCND1ALDH1A1HSD17B10 | |
| SCHEMBL30721419 | 0.72 | CDK4 (0.47) | CDK4CCND1ALDH1A1HSD17B10 | |
| SCHEMBL19041840 | 0.72 | CDK4 (0.38) | CDK4CCND1ALKALDH1A1HSD17B10 | |
| SCHEMBL26391992 | 0.72 | CDK4 (0.43) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL22894081 | 0.71 | CDK4 (0.54) | CDK4CCND1CCNB2CCNE2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810120-B | Carbazole-thienopyrazine derivative, preparation method, application and device thereof | 武汉尚赛光电科技有限公司 | 2020-10-30 | — | — | CN | disclosed |