Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.38 |
| ▸ | CCND1 | P24385 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14659482 | 0.83 | JAK2 (0.46) | CDK4CCND1GABRA1GABRG2GABRB3 | |
| SCHEMBL17285407 | 0.82 | AHR (0.50) | CDK4CCND1GABRA1GABRG2GABRB3 | |
| SCHEMBL18996708 | 0.82 | CRHBP (0.44) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL19041784 | 0.79 | KMT2A (0.44) | CDK4CCND1ALDH1A1CASP1HSD17B10 | |
| SCHEMBL24900353 | 0.76 | AHR (0.47) | CDK4CCND1GABRA1GABRG2GABRB3 | |
| SCHEMBL16745241 | 0.75 | CDK4 (0.51) | CDK4CCND1GABRA1GABRG2GABRB3 | |
| SCHEMBL17461223 | 0.75 | AHR (0.48) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL17118500 | 0.74 | AHR (0.41) | CDK4CCND1GABRA1GABRG2GABRB3 | |
| SCHEMBL16485102 | 0.74 | AHR (0.41) | CDK4CCND1GABRA1GABRG2GABRB3 | |
| SCHEMBL18045745 | 0.73 | L3MBTL1 (0.55) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017188597-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 두산 | 2017-11-02 | — | — | WO | disclosed |
| WO-2017111543-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 두산 | 2017-06-29 | — | — | WO | disclosed |