Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 18/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469640 | 0.85 | KDM1A (0.67) | KDM1AMEN1USP2LMNATP53 | |
| SCHEMBL28481400 | 0.84 | NPY5R (0.63) | KDM1AKDM4EMEN1LMNATP53 | |
| SCHEMBL28478208 | 0.83 | ABCG2 (0.56) | KDM1AKDM4EMEN1LMNATP53 | |
| SCHEMBL2258103 | 0.82 | KDM1A (0.71) | KDM1AKDM4EMEN1USP2LMNA | |
| SCHEMBL3347553 | 0.78 | KDM1A (1.00) | KDM1A | |
| SCHEMBL8908702 | 0.78 | NPY5R (0.74) | KDM1ANPC1PKMRAB9AKLF5 | |
| SCHEMBL28468206 | 0.78 | ABCG2 (0.61) | KDM1AKDM4EMEN1LMNATP53 | |
| SCHEMBL29569079 | 0.78 | MAPT (0.57) | KDM1AMEN1TP53MAPTKMT2A | |
| SCHEMBL12993921 | 0.78 | MAPT (0.57) | KDM1AMEN1TP53MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL8900394 | 0.77 | NPY5R (0.72) | KDM1ANPC1PKMRAB9AKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143693-A | 2-methylquinoline derivative with anti-tumor activity and synthesis method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | claimed |
| CN-111825610-A | 2-methylquinoline derivative with anti-tumor activity and synthesis method and application thereof | 中国药科大学 | 2020-10-27 | — | — | CN | claimed |
| CN-116143693-A | 2-methylquinoline derivative with anti-tumor activity and synthesis method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-111825610-B | 2-methylquinoline derivative with anti-tumor activity and synthesis method and application thereof | 中国药科大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-111825610-A | 2-methylquinoline derivative with anti-tumor activity and synthesis method and application thereof | 中国药科大学 | 2020-10-27 | — | — | CN | disclosed |