Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252026 | 0.83 | HPGD (0.79) | HPGDACHESIGMAR1BLMUSP2 | |
| SCHEMBL7129676 | 0.83 | HPGD (0.79) | HPGDACHESIGMAR1BLMUSP2 | |
| SCHEMBL13182763 | 0.82 | HPGD (0.66) | HPGDACHESIGMAR1BLMUSP2 | |
| SCHEMBL263534 | 0.82 | HPGD (0.66) | HPGDACHESIGMAR1BLMUSP2 | |
| Hydrochloric Acid SCHEMBL1597472 | 0.81 | HPGD (0.76) | HPGDACHESIGMAR1BLMUSP2 | |
| SCHEMBL7776187 | 0.81 | HPGD (0.63) | HPGDACHESIGMAR1BLMUSP2 | |
| SCHEMBL13901199 | 0.80 | HPGD (0.58) | HPGDACHESIGMAR1BLMUSP2 | |
| SCHEMBL1263133 | 0.79 | HPGD (0.88) | HPGDACHESIGMAR1BLMUSP2 | |
| SCHEMBL254870 | 0.79 | HPGD (0.96) | HPGDACHESIGMAR1BLMUSP2 | |
| SCHEMBL18228404 | 0.79 | HPGD (0.96) | HPGDACHESIGMAR1BLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112370452-A | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-107624111-B | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-11-03 | — | — | CN | disclosed |