SCHEMBL1263133

SCHEMBL1263133

O=C(c1ccccc1)N1CCC1

nearest known ligand 0.88

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 5/20 0.88
▸ ALDH1A1 P00352 2/20 0.75
▸ USP2 O75604 1/20 0.75
▸ MAPK1 P28482 1/20 0.71
▸ SIGMAR1 Q99720 1/20 0.68
▸ ACHE P22303 1/20 0.63
▸ L3MBTL1 Q9Y468 2/20 0.62
▸ L3MBTL3 Q96JM7 1/20 0.62
▸ LMNA P02545 1/20 0.62
▸ BLM P54132 1/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.59
▸ MAOB P27338 1/20 0.59
▸ TSHR P16473 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2614241 0.98 HPGD (0.84) HPGDALDH1A1USP2MAPK1SIGMAR1
SCHEMBL18228404 0.95 HPGD (0.96) HPGDALDH1A1USP2MAPK1SIGMAR1
SCHEMBL254870 0.95 HPGD (0.96) HPGDALDH1A1USP2MAPK1SIGMAR1
SCHEMBL8919062 0.93 HPGD (1.00) HPGDALDH1A1USP2MAPK1SIGMAR1
SCHEMBL1927946 0.93 HPGD (1.00) HPGDALDH1A1USP2MAPK1SIGMAR1
SCHEMBL243236 0.93 HPGD (1.00) HPGDALDH1A1USP2MAPK1SIGMAR1
SCHEMBL27929296 0.93 HPGD (1.00) HPGDALDH1A1USP2MAPK1SIGMAR1
SCHEMBL436090 0.93 HPGD (1.00) HPGDALDH1A1USP2MAPK1SIGMAR1
SCHEMBL2678752 0.92 HPGD (0.75) HPGDALDH1A1USP2MAPK1SIGMAR1
Hydrochloric Acid SCHEMBL9209631 0.91 HPGD (0.96) HPGDALDH1A1USP2MAPK1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382282-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2025-12-18 — — US disclosed
US-12398125-B2 Nitrogen-containing saturated heterocyclyl derivative Sumitomo Pharma Co., Ltd. (JP) 2025-08-26 — — US disclosed
EP-4563574-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLIC RING DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2025-06-04 — — EP disclosed
CN-119630649-A Nitrogen-containing saturated heterocyclic derivative 住友制药株式会社 2025-03-14 — — CN disclosed
US-20250051305-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2025-02-13 — — US disclosed
US-12172987-B2 Nitrogen-containing saturated heterocyclyl derivative Sumitomo Pharma Co., Ltd. (JP) 2024-12-24 — — US disclosed
US-20240124429-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2024-04-18 — — US disclosed
US-20220388979-A1 QUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS B.C.I. PHARMA (BE) 2022-12-08 — — US disclosed
WO-2021023888-A1 ISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS B.C.I. PHARMA (BE) 2021-02-11 — — WO disclosed
WO-2020132561-A1 TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2020-06-25 — — WO disclosed
US-4868288-A TITANIUM TETRACHLORIDE CATALYST CIBA-GEIGY CORPORATION (US) 1989-09-19 — — US disclosed
EP-0152377-B1 CURABLE COMPOSITIONS AND THEIR USE CIBA-GEIGY AG (CH) 1987-12-09 — — EP disclosed
EP-0094915-B1 CURABLE COMPOSITIONS CONTAINING METALLOCEN COMPLEXES, ACTIVATED PRIMERS OBTAINED THEREFROM AND THEIR USE CIBA-GEIGY AG (CH) 1987-01-21 — — EP disclosed
EP-0126712-B1 CURABLE COMPOSITION AND USE THEREOF CIBA-GEIGY AG (CH) 1986-12-10 — — EP disclosed
EP-0152377-A2 Curable compositions and their use CIBA-GEIGY AG (CH) 1985-08-21 — — EP disclosed
US-4528382-A Imidoyl substituted pyrroles MCNEILAB, INC. (US) 1985-07-09 — — US disclosed
EP-0126712-A1 Curable composition and use thereof CIBA-GEIGY AG (CH) 1984-11-28 — — EP disclosed
EP-0094915-A2 Curable compositions containing metallocen complexes, activated primers obtained therefrom and their use CIBA-GEIGY AG (CH) 1983-11-23 — — EP disclosed
US-4149941-A ELECTROLYTIC ALKOXYLATION HOECHST AKTIENGESELLSCHAFT (DE) 1979-04-17 — — US disclosed
US-4118500-A Fungicidal alkoxy mono- and dialkoxy N-substituted cyclic amines HOECHST AKTIENGESELLSCHAFT (DE) 1978-10-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388979-A1 QUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS ABL1, PHKB, EEF2K HPGD 2828/4885ALDH1A1 4455/4885USP2 1020/4885
US-20250382282-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE H1-0, HTT, PRNP HPGD 359/4885ALDH1A1 4022/4885USP2 1999/4885
US-12172987-B2 Nitrogen-containing saturated heterocyclyl derivative H1-0, HTT, PRNP HPGD 359/4885ALDH1A1 4022/4885USP2 1999/4885
US-12398125-B2 Nitrogen-containing saturated heterocyclyl derivative H1-0, HTT, PRNP HPGD 359/4885ALDH1A1 4022/4885USP2 1999/4885
US-20240124429-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE H1-0, HTT, PRNP HPGD 359/4885ALDH1A1 4022/4885USP2 1999/4885
US-20250051305-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE H1-0, HTT, PRNP HPGD 359/4885ALDH1A1 4022/4885USP2 1999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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