Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 14/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781878 | 0.84 | CASP3 (0.78) | CASP3GAAALDH1A1 | |
| SCHEMBL27781877 | 0.78 | CASP3 (1.00) | CASP3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27760312 | 0.76 | CASP3 (1.00) | CASP3KDM4EMAPT | |
| SCHEMBL27760323 | 0.76 | CASP3 (0.82) | CASP3KDM4EMEN1MAPTKMT2A | |
| SCHEMBL28196665 | 0.74 | CASP3 (0.64) | CASP3GAAKDM4EMEN1MAPT | |
| SCHEMBL28249477 | 0.73 | CASP3 (0.77) | CASP3MAPT | |
| SCHEMBL9208732 | 0.72 | CASP3 (0.66) | CASP3GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL27760311 | 0.72 | CASP3 (0.77) | CASP3GAAMAPTALDH1A1 | |
| SCHEMBL27781860 | 0.71 | CASP3 (1.00) | CASP3GAAALDH1A1 | |
| SCHEMBL28471683 | 0.70 | CASP3 (0.56) | CASP3GAAKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652218-B | Dihydropyrrolidone derivative and application thereof in preparation of antitumor drugs | 南方医科大学 | 2020-10-02 | — | — | CN | disclosed |