Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455009 | 0.78 | HPGD (0.46) | TSHRSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL28481025 | 0.77 | MEN1 (0.51) | TSHRSMN1; SMN2KDM1AMAOAKMT2A | |
| SCHEMBL5197638 | 0.77 | CA1 (0.47) | SMN1; SMN2KDM1AKMT2AMEN1CYP1A2 | |
| SCHEMBL28470650 | 0.76 | CA1 (0.38) | SMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL20288295 | 0.75 | KDM1A (0.48) | TSHRKDM1AMAOA | |
| SCHEMBL20288336 | 0.75 | KDM1A (0.53) | SMN1; SMN2KDM1AKMT2AMEN1CYP2C19 | |
| SCHEMBL15942452 | 0.75 | HPGD (0.49) | TSHRSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL16540222 | 0.74 | LIPG (0.38) | KMT2AMEN1 | |
| SCHEMBL34472141 | 0.74 | HSD17B10 (0.40) | TSHRKMT2AMEN1NPC1RAB9A | |
| SCHEMBL28472962 | 0.74 | CDK1 (0.38) | TSHRSMN1; SMN2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069728-A | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111868063-A | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2020-10-30 | — | — | CN | disclosed |