Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486078 | 0.84 | — | — | |
| SCHEMBL455887 | 0.79 | NQO1 (0.34) | — | |
| SCHEMBL2352053 | 0.77 | — | — | |
| SCHEMBL28473733 | 0.76 | MKNK1 (0.32) | — | |
| SCHEMBL28934386 | 0.74 | NQO1 (0.30) | — | |
| SCHEMBL28462684 | 0.73 | ALDH1A1 (0.32) | KDM4E | |
| SCHEMBL15067545 | 0.73 | SYK (0.33) | — | |
| SCHEMBL15067031 | 0.71 | HTR2C (0.38) | — | |
| SCHEMBL16395024 | 0.71 | POLB (0.41) | — | |
| SCHEMBL2498963 | 0.69 | KDM1A (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624113-B | Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of HBsAg (HBV surface antigen) and HBV DNA production for the treatment of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2020-10-23 | — | — | CN | disclosed |