Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | FLT4 | P35916 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22398008 | 1.00 | ERBB2 (0.49) | ERBB2MINK1FGFR1FLT1FGFR2 | |
| SCHEMBL26316601 | 0.91 | ERBB2 (0.51) | ERBB2MINK1FFAR1NPC1RAB9A | |
| SCHEMBL28472619 | 0.90 | ERBB2 (0.59) | ERBB2MINK1FFAR1 | |
| SCHEMBL22397911 | 0.90 | ERBB2 (0.59) | ERBB2MINK1FFAR1 | |
| SCHEMBL22398048 | 0.88 | ERBB2 (0.47) | ERBB2MINK1RAB9A | |
| SCHEMBL22398043 | 0.88 | ERBB2 (0.47) | ERBB2MINK1RAB9A | |
| SCHEMBL26316561 | 0.86 | ERBB2 (0.66) | ERBB2MINK1FGFR1FLT1FGFR2 | |
| SCHEMBL31130669 | 0.86 | ERBB2 (0.66) | ERBB2MINK1FGFR1FLT1FGFR2 | |
| SCHEMBL22398061 | 0.86 | ERBB2 (0.66) | ERBB2MINK1FGFR1FLT1FGFR2 | |
| SCHEMBL22398136 | 0.86 | ERBB2 (0.50) | ERBB2MINK1FGFR1FLT1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-A | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2020-11-03 | — | — | CN | disclosed |