Ethyne

Ethyne

SCHEMBL28470577

B.C#C.C#C.CC(C)(O)C(C)(C)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL402114 0.89 THRB (0.50) THRBALDH1A1TSHR
SCHEMBL21494164 0.89 THRB (0.50) THRBALDH1A1TSHR
SCHEMBL129302 0.89
SCHEMBL28434631 0.89 THRB (0.50) THRBALDH1A1TSHR
SCHEMBL21494162 0.84 THRB (0.46) THRBALDH1A1TSHR
SCHEMBL504018 0.84 THRB (0.55) THRBALDH1A1TSHR
SCHEMBL27028519 0.84 THRB (0.55) THRBALDH1A1TSHR
SCHEMBL8968 0.84
Water SCHEMBL3827178 0.78 THRB (0.50) THRBALDH1A1TSHR
SCHEMBL789340 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111819166-A Polycyclic aromatic compounds and methods of making and using the same 内华达高等教育系统董事会代表内华达大学雷诺分校 2020-10-23 CN disclosed