Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467462 | 0.83 | HRH3 (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL28593758 | 0.78 | MMP13 (0.67) | ALOX15MMP13RAB9AKDM4EALDH1A1 | |
| SCHEMBL2944272 | 0.77 | MMP13 (0.59) | MMP13RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL28687276 | 0.77 | MMP13 (0.81) | ALOX15MMP13RAB9AKDM4EALDH1A1 | |
| SCHEMBL2948163 | 0.76 | MMP13 (0.58) | MMP13RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL2951373 | 0.75 | MMP13 (0.60) | ALOX15MMP13RAB9AKDM4EALDH1A1 | |
| SCHEMBL2949503 | 0.75 | MMP13 (0.57) | MMP13RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL2943709 | 0.75 | HRH3 (0.66) | MMP13RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL28678169 | 0.75 | MMP13 (0.82) | ALOX15MMP13RAB9AKDM4EALDH1A1 | |
| SCHEMBL2951278 | 0.74 | MMP13 (0.56) | MMP13RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808079-A | Indole ASK1 small molecule inhibitor and preparation method and application thereof | 中国药科大学 | 2020-10-23 | — | — | CN | disclosed |