Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16161190 | 0.92 | TP53 (0.37) | TP53CYP3A4ALDH1A1KMT2A | |
| SCHEMBL27635533 | 0.91 | SLC6A2 (0.37) | TP53CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL16106877 | 0.86 | TP53 (0.44) | TP53CYP3A4ALDH1A1KMT2ATSHR | |
| SCHEMBL26977172 | 0.85 | TSHR (0.50) | TP53CYP3A4ALDH1A1HIF1AMAPK1 | |
| SCHEMBL27197216 | 0.83 | TP53 (0.41) | TP53CYP3A4ALDH1A1HIF1AMAPK1 | |
| SCHEMBL7261760 | 0.83 | CES2 (0.37) | TP53CYP3A4ALDH1A1HIF1AKMT2A | |
| SCHEMBL30776875 | 0.83 | CES2 (0.37) | TP53CYP3A4ALDH1A1HIF1AKMT2A | |
| SCHEMBL19283286 | 0.81 | CES2 (0.41) | ALDH1A1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL21917208 | 0.79 | KMT2A (0.40) | TP53CYP3A4ALDH1A1HIF1AKMT2A | |
| SCHEMBL16819123 | 0.79 | KMT2A (0.40) | TP53CYP3A4ALDH1A1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463493-B | Polymeric substrate having a surface with reduced biomolecule adhesion and thermoplastic articles of such substrate | SIO2医药产品公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-111971354-A | Foamed sheet | 日东电工株式会社 | 2020-11-20 | — | — | CN | disclosed |
| CN-111902506-A | Foamed sheet | 日东电工株式会社 | 2020-11-06 | — | — | CN | disclosed |
| CN-111902505-A | Foamed sheet | 日东电工株式会社 | 2020-11-06 | — | — | CN | disclosed |