Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 10/20 | 0.53 |
| ▸ | CCND1 | P24385 | 10/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29888691 | 0.87 | CDK4 (0.55) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL19494764 | 0.86 | CDK4 (0.56) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL29888674 | 0.85 | CDK4 (0.50) | CDK4CCND1GABRPGABRDGABRA1 | |
| SCHEMBL17277906 | 0.84 | IMPDH2 (0.49) | CDK4CCND1GABRPGABRDGABRA1 | |
| SCHEMBL28368134 | 0.82 | CDK4 (0.51) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL23668299 | 0.82 | CDK4 (0.47) | CDK4CCND1GABRPGABRDGABRA1 | |
| SCHEMBL30721419 | 0.82 | CDK4 (0.47) | CDK4CCND1GABRPGABRDGABRA1 | |
| SCHEMBL21104834 | 0.82 | CDK4 (0.50) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL19998255 | 0.81 | KMT2A (0.43) | CDK4CCND1CCNB2CCNE2CDK1 | |
| SCHEMBL21104502 | 0.81 | CDK4 (0.49) | CDK4CCND1CCNB2CCNE2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810120-B | Carbazole-thienopyrazine derivative, preparation method, application and device thereof | 武汉尚赛光电科技有限公司 | 2020-10-30 | — | — | CN | disclosed |