Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28899811 | 0.87 | NPC1 (0.52) | MEN1KMT2ATLR9KDM4ENPC1 | |
| SCHEMBL28465009 | 0.83 | NPC1 (0.68) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL28471161 | 0.83 | MEN1 (0.48) | MEN1KMT2ATLR9KDM4ENPC1 | |
| SCHEMBL28899889 | 0.82 | NPC1 (0.52) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL28463762 | 0.78 | NPC1 (0.55) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL28465287 | 0.78 | KMT2A (0.59) | MEN1KMT2ATLR9KDM4ENPC1 | |
| SCHEMBL28473184 | 0.78 | NPC1 (0.69) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL28470091 | 0.76 | RAB9A (0.53) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL6311013 | 0.76 | NPC1 (0.66) | MEN1KMT2AKDM4ENPC1MAPT | |
| SCHEMBL6311016 | 0.76 | NPC1 (0.66) | MEN1KMT2AKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675665-A | Styryl-containing quinoxalinone derivatives and preparation method thereof | 南京大学 | 2020-09-18 | — | — | CN | disclosed |