Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.86 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.86 |
| ▸ | HPGD | P15428 | 2/20 | 0.86 |
| ▸ | BLM | P54132 | 2/20 | 0.86 |
| ▸ | MAPT | P10636 | 1/20 | 0.86 |
| ▸ | IDO1 | P14902 | 1/20 | 0.86 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.86 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.79 |
| ▸ | FAAH | O00519 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylserotonin SCHEMBL28475510 | 1.00 | SPR (0.86) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| Acetylserotonin SCHEMBL30295379 | 0.93 | SPR (1.00) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| Acetylserotonin SCHEMBL29375184 | 0.93 | SPR (1.00) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| Acetylserotonin SCHEMBL422165 | 0.93 | SPR (1.00) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| Acetylserotonin SCHEMBL29669245 | 0.91 | SPR (0.97) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| Acetylserotonin SCHEMBL31488730 | 0.91 | SPR (0.97) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL1130740 | 0.89 | TRPV1 (0.78) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL1129809 | 0.89 | TRPV1 (0.78) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL23643317 | 0.88 | TRPV1 (1.00) | SPRNOTUMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL23630266 | 0.88 | TRPV1 (1.00) | SPRNOTUMKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111849934-A | Tue-sang-Dodecan-5-hydroxytryptamine oxygen methyltransferase and application thereof | 西南大学 | 2020-10-30 | — | — | CN | claimed |