Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718374 | 0.83 | CHRNA7 (0.55) | MAPTKDM4EALDH1A1ADRA2AADRA2B | |
| SCHEMBL8334018 | 0.80 | MAPT (0.49) | MAPTKDM4EALDH1A1PKMLMNA | |
| SCHEMBL188731 | 0.77 | KDM4E (0.61) | MAPTKDM4EALDH1A1PKM | |
| SCHEMBL21815733 | 0.77 | KDM4E (0.45) | MAPTKDM4EALDH1A1PKMADRA2A | |
| SCHEMBL5795262 | 0.75 | — | — | |
| SCHEMBL636365 | 0.73 | TSHR (0.37) | MEN1KMT2A | |
| SCHEMBL3923601 | 0.73 | — | — | |
| SCHEMBL188197 | 0.73 | CHRNA7 (0.66) | MAPTKDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL29204363 | 0.72 | TSHR (0.57) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL30767206 | 0.72 | TSHR (0.57) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107746405-B | SYK inhibitors | 吉利德科学公司 | 2020-09-22 | — | — | CN | disclosed |