⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636365 | 1.00 | TSHR (0.37) | — | |
| SCHEMBL8767704 | 0.89 | KDM4E (0.35) | — | |
| SCHEMBL1404051 | 0.89 | KDM4E (0.35) | — | |
| SCHEMBL841130 | 0.88 | — | — | |
| Sulfuric Acid SCHEMBL28081787 | 0.87 | TP53 (0.30) | — | |
| SCHEMBL4297694 | 0.87 | ALDH1A1 (0.38) | — | |
| SCHEMBL27854795 | 0.86 | MEN1 (0.39) | — | |
| SCHEMBL81243 | 0.86 | MEN1 (0.39) | — | |
| SCHEMBL12676697 | 0.85 | MAPT (0.32) | — | |
| SCHEMBL2316124 | 0.85 | DPP7 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| CN-1147498-C | Method for preparing oxazaphosphorin-2-amines | ASTAҩ��ɷݹ�˾ | 2004-04-28 | — | — | CN | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1312630-A1 | Process for the production of flexible polyurethane foams | Tosoh Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |
| CN-1268950-A | Method for preparing oxazaphosphorin-2-amines | ASTA MEDICA AG (DE) | 2000-10-04 | — | — | CN | disclosed |