SCHEMBL28474261

SCHEMBL28474261

CCCCCC(=O)ONc1cccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.51
KMT2A Q03164 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
HPGD P15428 2/20 0.49
ALDH1A1 P00352 1/20 0.49
EPHX1 P07099 1/20 0.48
CNR2 P34972 4/20 0.46
CNR1 P21554 3/20 0.46
CDC25A P30304 1/20 0.45
CDC25B P30305 1/20 0.45
CDC25C P30307 1/20 0.45
LMNA P02545 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27459826 0.84 HPGD (0.55) KDM4EKMT2AL3MBTL1CYP1A2CYP2C19
SCHEMBL31177113 0.81 P2RX7 (0.57) KMT2AHPGDALDH1A1HDAC3HDAC4
SCHEMBL28225591 0.81 P2RX7 (0.57) KMT2AHPGDALDH1A1HDAC3HDAC4
SCHEMBL31091435 0.78 EP300 (0.66) KDM4EKMT2AL3MBTL1CYP1A2CYP2C19
SCHEMBL3625990 0.78 KDM4E (0.44) KDM4EKMT2AHPGDALDH1A1LMNA
SCHEMBL6634874 0.78 P2RX7 (0.68) KDM4EKMT2AL3MBTL1EPHX1HDAC3
SCHEMBL8208778 0.78 P2RX7 (0.68) KDM4EKMT2AL3MBTL1EPHX1HDAC3
SCHEMBL28841581 0.78 SMN1; SMN2 (0.54) L3MBTL1CYP1A2CYP2C19ALDH1A1HDAC3
SCHEMBL1696044 0.76 KMT2A (0.50) KDM4EKMT2AL3MBTL1CYP1A2CYP2C19
SCHEMBL6750341 0.76 KDM4E (0.53) KDM4EKMT2ACYP1A2CYP2C19HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107375929-B Photosensitizer and derivatives and application thereof 大连理工大学 2020-10-30 CN disclosed