Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | MC3R | P41968 | 2/20 | 0.37 |
| ▸ | MC1R | Q01726 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893795 | 0.79 | ABCB1 (0.42) | ABCB1CA1CA2CA4CA9 | |
| SCHEMBL590923 | 0.75 | CA1 (0.62) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL28045116 | 0.75 | CA1 (0.62) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL29060292 | 0.73 | CA1 (0.46) | ABCB1CA1CA2CA4CA9 | |
| SCHEMBL3576211 | 0.72 | CA1 (0.54) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL2086686 | 0.72 | CA1 (0.54) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL1570873 | 0.72 | NR1H2 (0.49) | ABCB1DPP4 | |
| SCHEMBL1570869 | 0.72 | NR1H2 (0.49) | ABCB1DPP4 | |
| SCHEMBL21010215 | 0.72 | KDM4E (0.40) | ABCB1SLC6A2SLC6A4SLC6A3PSEN1 | |
| SCHEMBL18862950 | 0.71 | HSD11B1 (0.48) | ABCB1MC4RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111918651-A | GCN2 inhibitors and uses thereof | 默克专利股份有限公司 | 2020-11-10 | — | — | CN | disclosed |