Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290291 | 0.83 | CTSS (0.42) | MEN1KMT2AATRCTSSCA1 | |
| SCHEMBL20865565 | 0.80 | ATR (0.40) | MEN1KMT2AATRNPC1RAB9A | |
| SCHEMBL30810784 | 0.76 | ATR (0.36) | PRMT1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19776332 | 0.76 | ATR (0.36) | PRMT1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7011944 | 0.76 | MAPT (0.38) | PRMT1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL31124393 | 0.74 | ATR (0.37) | MEN1KMT2AATRCTSSCA1 | |
| SCHEMBL31124321 | 0.73 | ATR (0.41) | MAPTSMN1; SMN2MEN1KMT2AATR | |
| SCHEMBL31124503 | 0.73 | CA1 (0.39) | MEN1KMT2AATRCTSSCA1 | |
| SCHEMBL4591743 | 0.73 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29132832 | 0.73 | PRMT1 (0.39) | PRMT1MAPTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954663-A | Fluorinated 4- (substituted amino) phenyl carbamate derivatives | 赛弗卢尔生命科学公司 | 2020-11-17 | — | — | CN | disclosed |