SCHEMBL28475477

SCHEMBL28475477

CC(C)(C)c1cc(O)cc(C(C)(C)C)c1.[LiH]

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.94
GABRB2 P47870 1/20 0.94
LMNA P02545 2/20 0.50
TYR P14679 2/20 0.50
ALDH1A1 P00352 5/20 0.44
ALOX15 P16050 3/20 0.44
HSD17B10 Q99714 3/20 0.44
HPGD P15428 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP2C19 P33261 2/20 0.41
POLB P06746 1/20 0.40
MAPT P10636 3/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 1/20 0.39
PKM P14618 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18268 0.97 GABRA1 (1.00) GABRA1GABRB2LMNATYRALDH1A1
SCHEMBL28151410 0.94 GABRA1 (0.94) GABRA1GABRB2LMNATYRALDH1A1
Hydrochloric Acid SCHEMBL27539042 0.94 GABRA1 (0.94) GABRA1GABRB2LMNATYRALDH1A1
SCHEMBL14973413 0.94 GABRA1 (0.94) GABRA1GABRB2LMNATYRALDH1A1
Hydrochloric Acid SCHEMBL7075850 0.94 GABRA1 (0.94) GABRA1GABRB2LMNATYRALDH1A1
SCHEMBL29444798 0.94 GABRA1 (0.94) GABRA1GABRB2LMNATYRALDH1A1
SCHEMBL30897309 0.94 GABRA1 (0.94) GABRA1GABRB2LMNATYRALDH1A1
Hydrochloric Acid SCHEMBL6040025 0.92 GABRA1 (0.89) GABRA1GABRB2LMNATYRALDH1A1
SCHEMBL123887 0.91 GABRA1 (0.88) GABRA1GABRB2LMNATYRALDH1A1
SCHEMBL18353568 0.85 GABRA1 (0.76) GABRA1GABRB2LMNATYRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848668-B Pyridinylamino IVB group binuclear metal complex and preparation and application thereof 万华化学集团股份有限公司 2023-03-03 CN disclosed
CN-111848668-A Pyridinylamino IVB group binuclear metal complex and preparation and application thereof 万华化学集团股份有限公司 2020-10-30 CN disclosed