Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809413 | 0.83 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1 | |
| Bromide SCHEMBL2809451 | 0.82 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL5940467 | 0.77 | MAPT (0.64) | MAPTL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8187730 | 0.75 | ALDH1A1 (0.52) | MAPTL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2500053 | 0.75 | MAPT (0.56) | MAPTL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6185932 | 0.74 | ALDH1A1 (0.51) | MAPTL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24386889 | 0.74 | MAPT (0.60) | MAPTL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5793985 | 0.74 | ALDH1A1 (0.62) | MAPTL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10310251 | 0.74 | KMT2A (0.57) | MAPTSMN1; SMN2KMT2AMEN1HDAC1 | |
| SCHEMBL19704210 | 0.73 | MAPT (0.49) | MAPTL3MBTL1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111960970-B | Antitumor compounds | 中国人民解放军总医院 | 2021-08-20 | — | — | CN | disclosed |
| CN-108997172-B | Antitumor compounds | 中国人民解放军总医院 | 2020-12-15 | — | — | CN | disclosed |
| CN-111960970-A | Antitumor compounds | 中国人民解放军总医院 | 2020-11-20 | — | — | CN | disclosed |
| CN-111960985-A | Antitumor compounds | 中国人民解放军总医院 | 2020-11-20 | — | — | CN | disclosed |
| CN-111892516-A | Antitumor compounds | 中国人民解放军总医院 | 2020-11-06 | — | — | CN | disclosed |
| CN-111892517-A | Antitumor compounds | 中国人民解放军总医院 | 2020-11-06 | — | — | CN | disclosed |