Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | BCL6 | P41182 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655941 | 0.86 | SYK (0.74) | SYKABCG2TP53MAPTCDC7 | |
| SCHEMBL2627208 | 0.82 | SYK (0.54) | SYKABCG2MAPTZAP70 | |
| SCHEMBL2062260 | 0.80 | BCL6 (0.42) | EGFRBCL6CTSC | |
| SCHEMBL4175833 | 0.80 | BCL6 (0.56) | SYKMAPTEGFRBCL6CTSC | |
| SCHEMBL20752146 | 0.79 | LRRK2 (0.65) | SYKABCG2CDC7ZAP70CTSC | |
| SCHEMBL9945497 | 0.78 | EGFR (0.64) | EGFRBCL6CTSC | |
| SCHEMBL30394423 | 0.78 | CTSC (0.52) | SYKABCG2EGFRBCL6KDR | |
| SCHEMBL30378026 | 0.78 | BCL6 (0.48) | ABCG2EGFRBCL6CTSC | |
| SCHEMBL13669814 | 0.78 | BCL6 (0.48) | ABCG2EGFRBCL6CTSC | |
| SCHEMBL30394764 | 0.78 | EGFR (0.64) | EGFRBCL6CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111718325-A | 2,4, 5-substituted pyrimidine compound and preparation method and application thereof | 烟台药物研究所 | 2020-09-29 | — | — | CN | disclosed |